Masaryk University, the second largest university in the Czech Republic, is one of the foremost research-oriented Czech universities. i&i Prague is a biotech incubator and hub in the Central European Region, scouting and supporting projects with excellent innovative potential in the fields of MedTech, Diagnostics and Drug Discovery.
These two well-known organizations have joined forces working on the establishment of CasInvent Pharma, one of the first spin-offs of its kind, to enable further development of small-molecule compounds with anticancer properties. The core of the technology licensed to CasInvent from MU is a proprietary class of highly potent and selective inhibitors of casein kinases 1. These compounds are being developed for the treatment of selected types of leukemias, lymphomas and solid tumors. The entire team of CasInvent Pharma, including the laureates Vítězslav Bryja, Kamil Paruch, Radoslav Trautmann and further composed of Pavlína Janovská (MU) and David Stíbal (i&i Prague) is currently progressing their lead compound through the advanced stages of preclinical development.